Sir2002 is now released and has solved structures with up to 2000 atoms in the asymmetric unit. Refer to the main page for more information Compiling Sir97 seems to work uncannilly well, with no compilcations (at least on SGI IRIX 6.5.x) if you following the instructions. The following is adequately described in the README.TXT file that comes with Sir97. When you receive the tar file (sir97.tar), copy this into a directory where you would like this to be compiled and run from. extract the files from the tar file by using the command tar xvf sir97.tar Then uncompress all the resulting compressed *.Z files by typing uncompress *.Z Copy the SirWare.* files into your home directory (cp SirWare.* ~/) Compile the program by running make -f file_name where the file_name refers to your computer/OS type refered to in the README.TXT file. i.e., for SGI: make -f makefile.sgi for SUN: make -f makefile.sun for LINUX: make -f makefile.linux (If when compiling under Redhat 6.0 Linux (or any other linux), it fails complaining it cannot find libX11.a (as it can under Redhat Linux 6.0), edit the make file and under WLIBS substitute the path with the following: /usr/X11R6/lib/libX11.a) for FreeBSD 3.3 UNIX when using the f2c based F77 that comes with FreeBSD: Edit the makefile.linux file which can be adapted to FreeBSD Under WLIBX subsitute the given line with /usr/X11R6/lib/libX11.a Under FCOM substitute: f77 Under FOPT add: -Nx400 -Nn802 Under COPT add: -I /usr/X11R6/include Then to compile Sir97 type make -f makefile.linux Run the test file (sir97 loganin) to make sure sir97 is working. You can them create an alias for the program in your .cshrc file or put this directory in your path so it can be called from anywhere on your system.